CV-sida

Agneta Oskarsson

Agneta Oskarsson
Professor emerita i livsmedelstoxikologi

Presentation

Sedan 1994 professor i livsmedelstoxikologi vid Institutionen för biomedicin och veterinär folkhälsovetenskap, SLU. Tidigare chef vid toxikologiska laboratoriet, Livsmedelsverket, Director vid Reproductive Toxicology, AstraZeneca R&D, forakre vid Institutet för miljömedicin, Karolinska Institutet mm. Mångårig erfarenhet av toxikologisk riskbedömning av miljöföroreningar, naturliga toxiner, livsmedelstillsatser och aromämnen, bland annat som expert vid den europeiska livsmedelsmyndigheten EFSA.

Forskning

Kemiska hälsorisker i livsmedel och dricksvatten.

Utveckling och tillämpning av nya effektbaserade testmetoder för att identifiera kemiska hälsorisker och studera mekanismer för toxicitet.

Miljöanalys

Utveckling och tillämpning av effektbaserade in vitro-metoder för miljöanalys.

Publikationer i urval

1.        Lundqvist, J., Hellman, B. and Oskarsson, A.: The fungicide prochloraz induces oxidative stress and DNA damage in vitro. Food Chem. Toxicol., 91, 36-41, 2016.

2.        Yagdiran, Y., Oskarsson, A., Knight, C.H. and Tallkvist, J.: ABC- and SLC- transporters in murine and bovine mammary epithelium – effects of prochloraz. PLOS ONE, 11(3):e0151904, 2016.

3.        Oskarsson, A. Ullerås, E. and Ohlsson Andersson, Å.: Acetaminophen increases aldosterone secretion while suppressing cortisol and androgens – a possible link to increased risk of hypertension. Am. J. Hypertens., 29, 1158-1164, 2016.

4.        Oskarsson, A. and Ohlsson Andersson, Å.: Suppressed sex hormone biosynthesis by alkylresorcinols – a possible link to chemoprevention. Nutrition and Cancer: An International Journal, 68, 978-987, 2016.

5.        Yagdiran, Y., Tallkvist, J., Artursson, K. and Oskarsson, A.: Staphylococcus aureus and lipopolysaccharide modulate gene expressions of drug transporters in mouse mammary epithelial cells – correlation to inflammatory biomarkers. PLOS ONE, 11(9): e0161346, 2016.

6.        Continuing Education Course 4: Evaluation of Food Additives in Europe: Point of the Art. Eurotox 2016, Sevilla, Spain, Toxicology Lett., 258 Suppl, S7, 2016.

7.        Oskarsson, A., Yagdiran, Y., Nazemi, S., Tallkvist, J. and Knight, C.H.: Short communication: Staphylococcus aureus infection modulates expression of drug transporters and inflammatory biomarkers in mouse mammary gland. J. Dairy Sci., 100, 2375-2380, 2017.

8.        Lundqvist, J., Pekar, H., and Oskarsson, A.: Short communication: Microcystins activate nuclear factor erythroid 2–related factor 2 (Nrf2) in human liver cells in vitro – Implications for an oxidative stress induction by microcystins. Toxicon, 126, 47-50, 2017.

9.     Lundqvist, J., Tringali, C and Oskarsson, A.: Resveratrol, piceatannol and analogs inhibit activation of both wild-type and T877A mutant androgen receptor. J Steroid Biochem. Mol. Biol., 174, 161-168, 2017. Highlighted in Nature Reviews Urology, Fenner, A., 14 (11) 2017, p 642.

10.      Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2017. Re-evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives. EFSA Journal 2017;15(6):4786, 157 pp. doi:10.2903/j.efsa.2017.4786

11.      Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2017. Re-evaluation of sodium nitrate (E 251) as a food additive. EFSA Journal 2017;15(6):4787, 123 pp. doi:10.2903/j.efsa.2017.4787

12.     Oskarsson, A. as a member of the Working Group on Flavourings, 2017. Safety of benzophenone to be used as flavouring. EFSA Journal 2017;15(11):5012, 29 pp. doi:10.2903/j.efsa.2017.5012

13.      Oskarsson, A. as a member of the Working Group on Flavourings, 2017. Safety of ethyl acrylate to be used as flavouring. EFSA Journal 2017;15(11):5013, 33 pp. doi:10.2903/j.efsa.2017.5013

14.     Rosenmai, A. K., Ahrens, L., Le Godec, T., Lundqvist, J. and Oskarsson, A.: Relationship between peroxisome proliferator-activated receptor alpha activity and cellular concentration of 14 perfluoroalkyl substances in HepG2 cells. J. Appl. Toxicol., 38, 219-226, 2018.

15.     Rosenmai, A.K., Niss, F., Mandava, G., Lundqvist, J. and Oskarsson, A.: Impact of natural organic matter in water on in vitro bioactivity assays. Chemosphere, 200, 209-216, 2018.

16.     Niss, F., Rosenmai, A.K., Mandava, G., Örn, S., Oskarsson, A. and Lundqvist, J.; Short communication: Toxicity bioassays with concentrated cell culture media - a methodology to overcome the chemical loss by conventional preparation of water samples. Environ. Sci. Pollut. Res., 25, 12183-12188, 2018.

17.     Rosenmai, A. K., Lundqvist, J., Le Godec, T., Ohlsson, Å., Tröger, R., Hellman, B. and Oskarsson, A.: In vitro bioanalysis of drinking water from source to tap. Water Res., 139, 272-280, 2018.

18.     Probert, P.M., Leitch, A.C., Dunn, M.P., Meyer, S.K., Palmer, J.M., Abdelghany, T.M., Lakey, A.F., Cooke, M.P., Talbot, H., Wills, C., McFarlane, W., Blake, L.I., Rosenmai, A.K., Oskarsson, A., Figueiredo, R., Wilson, C., Kass, G.E., Jones, D.E., Blain, P.G. and Wright, M.C.: Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis. J. Hepatol., 69, 1123-1135, 2018. doi: 10.1016/j.jhep.2018.06.027

19.     Lungu-Mitea, S., Oskarsson, A. and Lundqvist, J.: Development of an oxidative stress in vitro assay in zebrafisk (Danio rerio) cell lines. Sci Rep., 2018 Aug 17;8 (1):12380. doi: 10.1038/s41598-018-30880-1.

20.     Rosenmai, A.K., Lundqvist, J., Gago-Ferrero, P., Mandava, G., Ahrens, L., Wiberg, K., and Oskarsson, A.: Effect-based assessment of recipient waters impacted by on-site, small scale, and large scale waste water treatment facilities – combining passive sampling with in vitro bioassays and chemical analysis. Scientific Reports, 2018 Nov 21; 8:17200. Doi:10.1038/s41598-018-35533-x

21.      Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Safety of hydroxyanthracene derivatives for use in food. EFSA Journal 2018;16(1):5088, 70 pp. doi:10.2903/j.efsa.2018.5088

22.      Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Scientific opinion on the safety of green tea catechins. EFSA Journal 2018;16(4):5239, 89 pp. doi:10.2903/j.efsa.2018.5239

23.     Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Re‐evaluation of aluminium sulphates (E 520-523) and sodium aluminium phosphate (E 541) as food additives. EFSA Journal 2018;16(7):5372, 40 pp. doi:10.2903/j.efsa.2018.5372

24.     Alexander, J. and Oskarsson, A.: Toxic metals. In Chemical Hazards in Food of Animal Origin. Food Safety Assurance and Veterinary Public Health No.7. F.J.M. Smulders, I.M.C.M. Rietjens and M.D. Rose, eds. Wageningen Academic Publishers, 2019, The Netherlands, pp 157-180.

25.     Lundqvist, J., Andersson, A., Johannisson, A., Lavonen, E., Mandava, G., Kylin, H., Bastviken, D. and Oskarsson, A.: Innovative drinking water treatment techniques reduce dissolved organic carbon (DOC) and the disinfection-induced oxidative stress and genotoxic activity. Water Res., 155, 182-192, 2019.

26.     Lundqvist, J., Helmersson, E. and Oskarsson, A.: Hormetic effect of NaAsO2 on proliferation of prostate cells in vitro – implications for prostate cancer initiation and therapy. Dose-Response, 17 (2), 1-6, 2019, doi: 10.1177/1559325819843374.

27.     Lundqvist, J., von Brömssen, C., Rosenmai, A.K., Ohlsson Å., Le Godec, T., Jonsson, O., Kreuger, J. and Oskarsson, A.: Assessment of pesticides in surface water samples from Swedish agricultural areas by integrated bioanalysis and chemical analysis. Environ. Sci. Eur., 31:53, 2019, doi.org/10.1186/s12302-019-0241-x. 

28.     Oskarsson, A. and Wright, M.C.: Ionic liquids: New emerging pollutants, similarities with perfluorinated alkyl substances (PFASs). Environ. Sci. Technol., 53, 10539-10541, 2019, doi: 10.1021/acs.est.9b04778.

29.      Oskarsson, A. as a member of the EFSA Panel on Food Additives and Flavourings (FAF), 2019. Scientific Opinion on Flavouring Group Evaluation 501 (FGE.501): Grill flavour concentrate (vegetable). EFSA Journal 2019;17(5):5675, 57 pp. doi:10.2903/j.efsa.2019.5675

30.     Leitch, A.C., Abdelghany, T.M., Probert, P.M., Dunn, M.P., Meyer, S.K., Palmer, J.M., Cooke, M.P., Blake, L.I., Morse, K., Rosenmai, A.K., Oskarsson, A., Bates, L., Figueiredo, R.S., Ibrahim, I., Wilson, C., Abdelkader, N.F., Jones, D.E., Blain, P.G. and Wright, M.C.: The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects. Food Chem. Toxicol., 136, 111069, 2020, doi: 10.1016/j.fct.2019.111069.

 

 

 

 

 

 

 

 

 

 

 

 


Kontaktinformation
Forskare vid Institutionen för biomedicin och veterinär folkhälsovetenskap (BVF); Enheten för farmakologi och toxikologi
Telefon: +4618673533
Postadress:
BVF, Avd för farmakologi och toxikologi, Box 7028
75007 UPPSALA
Besöksadress: Ulls väg 26, Uppsala