Agneta Oskarsson
Presentation
Sedan 1994 professor i livsmedelstoxikologi vid Institutionen för biomedicin och veterinär folkhälsovetenskap, SLU. Tidigare chef vid toxikologiska laboratoriet, Livsmedelsverket; Director vid Reproductive Toxicology, AstraZeneca R&D; forskare vid Institutet för miljömedicin, Karolinska Institutet mm. Mångårig erfarenhet av toxikologisk riskbedömning av miljöföroreningar, naturliga toxiner, livsmedelstillsatser och aromämnen, bland annat som expert vid den europeiska livsmedelsmyndigheten EFSA.
Forskning
Kemiska hälsorisker i livsmedel och dricksvatten.
Utveckling och tillämpning av nya effektbaserade testmetoder för att identifiera kemiska hälsorisker och studera mekanismer för toxicitet.
Publikationer i urval
1. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Flavourings (FAF), 2020. Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources (Revision 1). EFSA Journal 2021;19(3):6552, 39 pp. doi:10.2903/j.efsa.2021.6552
2. Oskarsson, A., Rosenmai, A.K., Mandava, G., Johannisson, A., Holmes, A., Tröger, R., and Lundqvist, J.: Assessment of source and treated water quality in seven drinking water treatment plants by in vitro bioassays – oxidative stress and antiandrogenic effects after artificial infiltration. Sci. Total Environ., 4;758:144001, 2021. doi: 10.1016/j.scitotenv.2020.144001
3. Lundqvist, J., Persson, K.M., and Oskarsson, A.: Glass-bottled drinking water – a time capsule to study the historic presence of hazardous chemicals using effect-based methods. Environ. Sci. Eur., 33:34, 2021, doi.org/10.1186/s12302-021-00476-0
4. Selin, E., Svensson, K., Gravenfors, E., Giovanoulis, G., Oskarsson, A., Lundqvist, J.: Food contact materials: an effect-based evaluation of the presence of hazardous chemicals in paper and cardboard. Fd. Add. Contam., Part A, 2021. doi.org/10.1080/19440049.2021.1930200.
5. Celma, A., Mandava, G., Oskarsson, A., Sancho, J.V., Bijlsma, L. and Lundqvist, J.: In vitro bioanalytical assessment of toxicity of wetland samples from Spanish Mediterranean coastline. Environ. Sci. Eur., 33:70, 2021. doi.org/10.1186/s12302-021-00510-1.
6. Persson, K.M., Lundqvist, J. och Oskarsson, A.: Vad har hänt med vårt dricksvatten på 30 år? Svenskt Vatten Utveckling. Rapport Nr 2021-7.
7. Yu, M., Lavonen, E., Oskarsson, A. and Lundqvist, J.: Removal of oxidative stress and genotoxic activities during drinking water production by ozonation and granular activated carbon filtration. Environ. Sci. Eur., 33:124, 2021. doi.org/10.1186/s12302-021-00567-y.
8. Selin, E., Mandava, G., Vilcu, A.-L., Oskarsson, A. and Lundqvist, J.; An in vitro-based assessment of liquid smoke flavourings. Arch. Toxicol., 96, 601–611, 2022. doi.org/10.1007/s00204-021-03190-1.
9. Oskarsson, A. and Alexander, J.: Chapter 7. Toxic Metals in Food. In: Volume I. Handbook on the Toxicology of Metals, 5th edition, G.F. Nordberg and M. Costa. Elsevier, Amsterdam, 2021, pp 183-207.
10. Oskarsson, A.: Chapter 4. Barium. In: Volume II. Handbook on the Toxicology of Metals, 5th edition, G.F. Nordberg and M. Costa. Elsevier, 2021, 91-100.
11. Albin, M. and Oskarsson, A.: Chapter 23. Molybdenum. In: Volume II. Handbook on the Toxicology of Metals, 5th edition, G.F. Nordberg and M. Costa. Elsevier, 2021, 601-614.
12. Lungu-Mitea, S., Vogs, C., Carlsson,C., Montag, M., Friberg, K., Oskarsson, A., and Lundqvist, J.: Modelling bioavailable concentrations in zebrafish cell lines and embryos increases the correlation of toxicity potencies across test systems. Environ. Sci. Technol., 55, 447-457, 2021.
13. Leitch, A.C., Abdelghany, T.M., Probert, P.M., Dunn, M.P., Meyer, S.K., Palmer, J.M., Cooke, M.P., Blake, L.I., Morse, K., Rosenmai, A.K., Oskarsson, A., Bates, L., Figueiredo, R.S., Ibrahim, I., Wilson, C., Abdelkader, N.F., Jones, D.E., Blain, P.G. and Wright, M.C.: The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects. Food Chem. Toxicol., 136, 111069, 2020, doi: 10.1016/j.fct.2019.111069.
14. Alexander, J. and Oskarsson, A.: Toxic metals. In Chemical Hazards in Food of Animal Origin. Food Safety Assurance and Veterinary Public Health No.7. F.J.M. Smulders, I.M.C.M. Rietjens and M.D. Rose, eds. Wageningen Academic Publishers, 2019, The Netherlands, pp 157-180.
15. Lundqvist, J., Andersson, A., Johannisson, A., Lavonen, E., Mandava, G., Kylin, H., Bastviken, D. and Oskarsson, A.: Innovative drinking water treatment techniques reduce dissolved organic carbon (DOC) and the disinfection-induced oxidative stress and genotoxic activity. Water Res., 155, 182-192, 2019.
16. Lundqvist, J., Helmersson, E. and Oskarsson, A.: Hormetic effect of NaAsO2 on proliferation of prostate cells in vitro – implications for prostate cancer initiation and therapy. Dose-Response, 17 (2), 1-6, 2019, doi: 10.1177/1559325819843374.
17. Lundqvist, J., von Brömssen, C., Rosenmai, A.K., Ohlsson Å., Le Godec, T., Jonsson, O., Kreuger, J. and Oskarsson, A.: Assessment of pesticides in surface water samples from Swedish agricultural areas by integrated bioanalysis and chemical analysis. Environ. Sci. Eur., 31:53, 2019, doi.org/10.1186/s12302-019-0241-x.
18. Oskarsson, A. and Wright, M.C.: Ionic liquids: New emerging pollutants, similarities with perfluorinated alkyl substances (PFASs). Environ. Sci. Technol., 53, 10539-10541, 2019, doi: 10.1021/acs.est.9b04778.
19. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Flavourings (FAF), 2019. Scientific Opinion on Flavouring Group Evaluation 501 (FGE.501): Grill flavour concentrate (vegetable). EFSA Journal 2019;17(5):5675, 57 pp. doi:10.2903/j.efsa.2019.5675
20. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Re‐evaluation of aluminium sulphates (E 520-523) and sodium aluminium phosphate (E 541) as food additives. EFSA Journal 2018;16(7):5372, 40 pp. doi:10.2903/j.efsa.2018.5372
21. Rosenmai, A. K., Ahrens, L., Le Godec, T., Lundqvist, J. and Oskarsson, A.: Relationship between peroxisome proliferator-activated receptor alpha activity and cellular concentration of 14 perfluoroalkyl substances in HepG2 cells. J. Appl. Toxicol., 38, 219-226, 2018.
22. Rosenmai, A.K., Niss, F., Mandava, G., Lundqvist, J. and Oskarsson, A.: Impact of natural organic matter in water on in vitro bioactivity assays. Chemosphere, 200, 209-216, 2018.
23. Niss, F., Rosenmai, A.K., Mandava, G., Örn, S., Oskarsson, A. and Lundqvist, J.; Short communication: Toxicity bioassays with concentrated cell culture media - a methodology to overcome the chemical loss by conventional preparation of water samples. Environ. Sci. Pollut. Res., 25, 12183-12188, 2018.
24. Rosenmai, A. K., Lundqvist, J., Le Godec, T., Ohlsson, Å., Tröger, R., Hellman, B. and Oskarsson, A.: In vitro bioanalysis of drinking water from source to tap. Water Res., 139, 272-280, 2018.
25. Probert, P.M., Leitch, A.C., Dunn, M.P., Meyer, S.K., Palmer, J.M., Abdelghany, T.M., Lakey, A.F., Cooke, M.P., Talbot, H., Wills, C., McFarlane, W., Blake, L.I., Rosenmai, A.K., Oskarsson, A., Figueiredo, R., Wilson, C., Kass, G.E., Jones, D.E., Blain, P.G. and Wright, M.C.: Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis. J. Hepatol., 69, 1123-1135, 2018. doi: 10.1016/j.jhep.2018.06.027
26. Lungu-Mitea, S., Oskarsson, A. and Lundqvist, J.: Development of an oxidative stress in vitro assay in zebrafisk (Danio rerio) cell lines. Scientific Reports, 2018 Aug 17;8 (1):12380. doi: 10.1038/s41598-018-30880-1.
27. Rosenmai, A.K., Lundqvist, J., Gago-Ferrero, P., Mandava, G., Ahrens, L., Wiberg, K., and Oskarsson, A.: Effect-based assessment of recipient waters impacted by on-site, small scale, and large scale waste water treatment facilities – combining passive sampling with in vitro bioassays and chemical analysis. Scientific Reports, 2018 Nov 21; 8:17200. Doi:10.1038/s41598-018-35533-x
28. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Safety of hydroxyanthracene derivatives for use in food. EFSA Journal 2018;16(1):5088, 70 pp. doi:10.2903/j.efsa.2018.5088
29. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2018. Scientific opinion on the safety of green tea catechins. EFSA Journal 2018;16(4):5239, 89 pp. doi:10.2903/j.efsa.2018.5239
30. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2017. Re-evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives. EFSA Journal 2017;15(6):4786, 157 pp. doi:10.2903/j.efsa.2017.4786
31. Oskarsson, A. as a member of the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), 2017. Re-evaluation of sodium nitrate (E 251) as a food additive. EFSA Journal 2017;15(6):4787, 123 pp. doi:10.2903/j.efsa.2017.4787
32. Lundqvist, J., Pekar, H., and Oskarsson, A.: Short communication: Microcystins activate nuclear factor erythroid 2–related factor 2 (Nrf2) in human liver cells in vitro – Implications for an oxidative stress induction by microcystins. Toxicon, 126, 47-50, 2017.
33. Lundqvist, J., Tringali, C and Oskarsson, A.: Resveratrol, piceatannol and analogs inhibit activation of both wild-type and T877A mutant androgen receptor. J Steroid Biochem. Mol. Biol., 174, 161-168, 2017. Highlighted in Nature Reviews Urology, Fenner, A., 14 (11) 2017, p 642.
34. Oskarsson, A. as a member of the Working Group on Flavourings, 2017. Safety of benzophenone to be used as flavouring. EFSA Journal 2017;15(11):5012, 29 pp. doi:10.2903/j.efsa.2017.5012
35. Oskarsson, A. as a member of the Working Group on Flavourings, 2017. Safety of ethyl acrylate to be used as flavouring. EFSA Journal 2017;15(11):5013, 33 pp. doi:10.2903/j.efsa.2017.5013
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