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Maria Östman

Maria Östman
Research student at the Faculty of Veterinary Medicine Dept. of Clinical Sciences; small animal surgery. Strong interest in translational medicine, neuroscience and surgery. Currently evaluating a new biomaterial in a spinal fusion animal model.

Presentation

My path within medicine started out in the human medical sciences, specifically within the field of neuroscience and addiction medicine. I earned a Master in Medical Science 2014 from Karolinska Institute. My thesis was written in collaboration with Icahn School of Medicine at Mount Sinai in New York reporting on the effect of Cannabidiol on craving in opioid dependent individuals. After working with bioprocess engineering in a biomedical company, I took the chance to enter the field of veterinary medical sciences. I earned a Doctor in Veterinary Medicine from University of Veterinary Medicine and Pharmacy in Kosice, Slovakia 2020. I worked as a veterinarian at the SLU University Hospital (UDS) before starting my research studies in Nov 2020 at the Department of Clinical Sciences; small animal surgery. 

Undervisning

Part-time university adjunct (universitetsadjunkt) within small animal surgery. 

Forskning

Doctoral Project - Spinal Fusion

Spinal fusion surgeries are commonly performed procedures in both veterinary and human medicine. However, complete intervertebral fusion is not always achieved. Incomplete intervertebral fusion may lead to increased patient morbidity and surgical failure.   

The main focus of my licentiate project is to evaluate a novel ceramic biomaterial, developed at Uppsala University, to facilitate cervical spinal fusion in an animal model.

The first part of the licentiate project includes evaluating the ceramic biomaterial using a pig animal model. Intervertebral fusion will be evaluated in vivo using traditional computed tomography (CT) and CT micromotion analysis (CTMA), therafter ex vivo using μCT and hard tissue histology. The second part of the project inlcudes a canine cadaver-study evaluating the application method of the ceramic biomaterial. 

The project has a strong translational approach and is a collaboration between SLU and Uppsala University. 

Supervisors

- Odd Höglund - Associate Professor, SLU Faculty of Veterinary Medicine Dept. of Clinical Sciences; small animal surgery

- Franck Forterre - Guest Professor, SLU Faculty of Veterinary Medicine Dept. of Clinical Sciences; small animal surgery and Professor, University of Bern, Switzerland

- Patricia Hedenqvist - Researcher, SLU Faculty of Veterinary Medicine Dept. of Clinical Sciences

- Håkan Engqvist - Professor, Uppsala University Dept. of Materials Science and Engineering, Applied Material Science

- Peter Försth - M.D. Head of Spine Surgery Unit, Uppsala University Hospital Department of Orthopedics

Publikationer i urval

Yasmin L. Hurd, Michelle Yoon, Alex F. Manini, Stephanie Hernandez, Ruben Olmedo, Maria Ostman and DidierJutras-Aswad. "Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage." Neurotherapeutics 12, 807–815 (2015). https://doi.org/10.1007/s13311-015-0373-7

Early Phase In the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage.


Kontaktinformation

Doktorand vid Institutionen för kliniska vetenskaper (KV); Smådjurskirurgi
Telefon: +4618671203