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Claudia Lützelschwab

Claudia Lützelschwab
I have extensive experience in a wide range of molecular biology and immunological techniques with a special interest in developing novel diagnostics and prognostic biomarkers and implementation of these methods for clinical use.

Presentation

Degrees:

Veterinarian. Faculty of Veterinary Science (FCV), National University of the Centre of Buenos Aires Province (UNCPBA). Tandil, Argentina (March 1984).

Doctor in Medical Science (PhD). Department of Immunology and Medical Microbiology (IMIM), Faculty of Medicine, Uppsala University (UU). Uppsala, Sweden (September 1997).

 

1998-2020

Assistant professor. Department of Animal Health and Preventive Medicine (SAMP), Faculty of Veterinary Science, UNCPBA, Tandil. Formal pedagogical training and education.

2020-

 

Researcher at Swedish Agricultural University. Department of Biomedical Sciences and Veterinary Public Health, Immunology and Pathology groups.

Undervisning

Undergraduate teaching:

At the Faculty of Veterinary Science, UNCPBA, Argentina:

1980-1982

Histology and Embryology

1984-1992

Animal Physiology

1998-2004

Basic Immunology, Special Immunology and Parasitology and Parasitic Diseases

2005- 2019

Basic Immunology

At the Faculty of Medicine, Uppsala University, Sweden:

1991-1997

Immunology (for biomedicine and pharmacy students)

Post graduate teaching (PhD program in Animal Science, Faculty of Veterinary Science, UNCPBA, Argentina)

2008- 2015

Advanced Immunology (Course Director and lecturer)

2010-2017

Immunological Techniques in the Biomedical Sciences (Course Director and Lecturer)

Forskning

Ongoing research activities:

• Biomarkers that differentiate bacterial from viral infections to reduce antimicrobial misuse

• Diagnostic biomarkers for early detection of joint diseases in horses

• Immune response to experimental vaccines

Publikationer i urval

Skiöldebrand, E., S. Adepu, C. Lützelschwab, S. Nyström, A. Lindahl, K. Abrahamsson-Aurell and E. Hansson. "A randomized, triple-blinded controlled clinical study with a novel disease-modifying drug combination in equine lameness-associated osteoarthritis". 2023. Osteoarthr Cartil Open 5(3): 100381. https://doi.org/10.1016/j.ocarto.2023.100381 

Kendall, A., C. Lützelschwab, J. Lundblad and E. Skiöldebrand. "Serum nerve growth factor in horses with osteoarthritis-associated lameness". 2023. Journal of Veterinary Internal Medicine 37(3): 1201-1208. https://doi.org/10.1111/jvim.16718

Adepu, S., M. Lord, Z. Hugoh, S. Nystrom, L. Mattsson-Hulten, K. Abrahamsson-Aurell, C. Lützelschwab and E. Skioldebrand. "Salivary biglycan-neo-epitope-BGN(262): A novel surrogate biomarker for equine osteoarthritic sub-chondral bone sclerosis and to monitor the effect of short-term training and surface arena". 2023. Osteoarthr Cartil Open 5(2): 100354. https://doi.org/10.1016/j.ocarto.2023.100354

Morán, M. C., M. P. Domínguez, A. R. Bence, M. G. Rodríguez, F. A. Goldbaum, V. Zylberman, P. R. Paola, G. Lupi, I. S. Marcipar, C. M. Lützelschwab and S. M. Estein. "Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA) administered by parenteral or mucosal routes against Brucella ovis in BALB/c mice". 2022. Research in Veterinary Science 145: 29-39. https://doi.org/10.1016/j.rvsc.2022.02.001

Morán M. C., Bence A. R.; Sánchez Vallecillod, M. F.; Lützelschwab, C. M.; Rodriguez, M. G.; Pardog, R.; Goldbaum F. A.; Zylberman, V.; Palmah, S. D.; M. Maletto, B. A., Estein, S. M “Polymeric antigen BLSOmp31 formulated with Class B CpG-ODN in a nanostructure (BLSOmp31/CpG-ODN/Coa-ASC16) administered by parenteral or mucosal routes confers protection against Brucella ovis in Balb/c mice”. 2021. Res Vet Sci  Vol. 135: 217-227. http://doi.org/10.1016/j.rvsc.2021.02.011

Hjertner, B.; Lützelschwab, C.; E. Schieck, Nzau, B.; Henson, S.; Sjölund, M.; Fossum C. and Magnusson, U. "Development of a 3-transcript host expression assay to differentiate between viral and bacterial infections in pigs". 2021. PLOS ONE 16(9): e0256106. http://doi.org/10.1371/journal.pone.0256106

Forletti, A.; Lützelschwab, C.; Cepeda, R. Esteban, E. and Gutiérrez, S.  “Early events following Bovine Leukaemia Virus infection in calves with different alleles of the major histocompatibility complex DRB3 gene”. 2020. Veterinary Research. 51: 4, 1-12. https://doi.org/10.1186/s13567-019-0732-1

Juliarena, M.A., Barrios, C.N., Lützelschwab, C.M., Esteban, E.N. and Gutiérrez, S.E. “Bovine Leukaemia Virus: current perspectives”. 2017. Virus Adaptation and Treatment, 9:13-26. http://dx.doi.org/10.2147/VAAT.S113947

Lϋtzelschwab C.M., Forletti, A., Cepeda, R., Esteban, E.N., Confalonieri, O.R. and Gutiérrez, S.E. "Co-infection with Mycobacterium bovis does not alter the response to Bovine Leukaemia Virus in BoLA DRB3 *0902, genetically resistant cattle". 2016. Research in Veterinary Science, Vol 109:10-16. ISSN: 0034-5288. http://dx.doi.org/10.1016/j.rvsc.2016.09.002 

Gutiérrez, S.E., Lützelschwab, C.M., Díaz, A.G. and Estein, S.M. “Fluorescence polarization assay for the diagnosis of anti-Brucella abortus antibodies in cattle serum: adaptation for its use in microplates and comparison with conventional agglutination tests". 2014. J. Vet. Sci. Med. Diag 3:3. ISSN: 2325-9590. Https://doi.org/10.4172/2325-9590.1000140

Books and book chapters.

2016

Gutiérrez, S.E., Esteban, E.N., Lϋtzelschwab C.M. and Juliarena, M.A. Trends and Advances in Veterinary Genetics, Dr. Muhammad Abubakar (Ed.), InTech, DOI: 10.5772/65804. ISBN 978-953-51-4921-7.

Available from: https://www.intechopen.com/books/trends-and-advances-in-veterinary-genetics/major-histocompatibility-complex-associated-resistance-to-infectious-diseases-the-case-of-bovine-leu

2009

Esteban, E.N., Poli, M., Poiesz, B., Ceriani, C., Dube, S, Gutiérrez, S, Dolcini, G., Gagliardi, R., Pérez, S., Lϋtzelschwab C.M., Feldman, L. and Juliarena, M.A. BLV control by selecting breeding. In: Animal Genetic. Nova Science Publishing. EDS: Hauppauge New York United States. 25 pages. ISBN: 978-1-60741-844-3.

2007

Lϋtzelschwab, C.M. Nematodes: immunity. In: Parasitic diseases of sheep and other ruminants in Southern America, Ed. V. Suarez, F. Olaechea, C. Rossanigo, J. Romero Publ. Technique 70; ISBN 03252132; 298 p. Anguil, Argentina. 14 pages (145-158). (in Spanish)


Kontaktinformation

Forskare vid Institutionen för husdjurens biovetenskaper (HBIO); HBIO, Patologi och immunologi
Telefon: +4618672325
Postadress:
Institutionen för husdjurens biovetenskaper (HBIO)
Box 7023
750 07 UPPSALA
Besöksadress: Ulls väg 26, Uppsala