CV page

Sarah Muniz Nardeli

Sarah Muniz Nardeli
Almost all protein-coding genes and many long non-coding RNA genes are transcribed by RNA polymerase II (RNA Pol II), and its transcriptional speed, or elongation rate, is a major determinant of transcriptome composition. It controls co-transcriptional processes such as splicing, polyadenylation, and transcription termination, thus regulating the production of alternative spliced variants, circular RNAs, alternatively polyadenylated transcripts, or read-through transcripts. RNA Pol II speed itself is regulated in response to intra- and extra-cellular stimuli and can in turn affect the transcriptome composition in response to these stimuli. I study the important role of transcription to adaptation of cells and organisms to a changing environment.

Background

- since 2024: Researcher, SLU, Uppsala, Sweden.
- 2020-2024: Postdoctoral Researcher, Umeå Plant Science Centre, Umeå University, Umeå, Sweden.
- 2015-2019: Doctor of Philosophy - PhD, Genetics, Federal University of Rio de Janeiro, Brazil.
- 2012-2015: Life Sciences Consultant, Atlantis Biotecnologia. Brazil.
- 2011-2012: Researcher, Università degli Studi di Milano, Milan, Italy.

Selected publications

- NARDELI, SARAH MUNIZ; El Arbi, N.; Dikaya, V.; Rojas-Murcia, N. ; Goretti, G.; Schmid, M. Time and temperature-resolved transcriptomic analysis of Arabidopsis splicing-related mutants. bioRxiv, 2024. DOI: https://doi.org/10.1101/2024.11.08.622454

- Meena, S.K.; Quevedo, M.; NARDELI, SARAH MUNIZ; Verez, C.; Bhat, S.S.; Zacharaki, V.; Kindgren, P. Antisense transcription from stress-responsive transcription factors fine-tunes the cold response in Arabidopsis. The Plant Cell, 2024. DOI: 10.1093/plcell/koae160

- NARDELI, SARAH MUNIZ; Zacharaki, V.; Rojas-Murcia, N.; Collani, S. Kai Wang, K.; Bayer, M.; Schmid, M.; Goretti, D. Arabidopsis thaliana LSM7 is essential for auxin-mediated regulation of SAUR genes and thermomorphogenesis. bioRxiv, 2023; DOI: https://doi.org/10.1101/2023.03.28.534379

-El Arbi, N.; NARDELI, SARAH MUNIZ; Šimura, J.; Ljung, K.; Schmid, M. The Arabidopsis splicing factor PORCUPINE/SmE1 orchestrates temperature-dependent root development via auxin homeostasis maintenance. New Phytologist, 2024. DOI: https://doi.org/10.1111/nph.20153

- Goretti, D.; Collani, S.; NARDELI, SARAH MUNIZ; Schmid, M. Methylosome and SMN complexes are dispensable for snRNP assembly in Arabidopsis. bioRxiv, 2023. DOI: https://doi.org/10.1101/2023.09.06.556483

- Dikaya, V.; El Arbi, N.; Rojas-Murcia, N.; NARDELI, SARAH MUNIZ; Goretti, D.; Schmid, M. Insights into the role of alternative splicing in plant temperature response. JOURNAL OF EXPERIMENTAL BOTANY, v. 72, p. 7384, 2021. DOI: 10.1093/jxb/erab234

 

Related pages:

Contact

Researcher at the Department of Plant Biology; Mol. cellbiologi
Telephone: +4618673234, +46704365303
E-mail: sarah.nardeli@slu.se
Postal address:
Inst för växtbiologi, Box 7080
750 07 Uppsala
Visiting address: Almas Allé 5, BioCentrum, Uppsala